Week 4 opens with Steelers at Browns Thursday and builds into a full Sunday slate.
Pittsburgh is around -2.5 at Cleveland with a low total near 37.5.
Patriots at Bills, Rams at Eagles, Packers at Buccaneers, Chiefs at Raiders and Broncos at 49ers are among the key games.
Steelers -2.5 and Bills -6.5 are two of this week’s seven official predictions.