A ranked Saturday features multiple matchups with playoff and conference implications.
Alabama is around -5.5 in a matchup of ranked SEC teams.
Notre Dame is 4-0 and favored by roughly 20.5 points after a 49-10 win over Purdue.
Ohio State is around -13.5 on the road against unbeaten Iowa.
Unbeaten Miami is around -16.5 at Clemson after the Tigers won 24-10 at California.